Hypothermia in neuronal protection

Alkan T., Bekar A., Korfali E.

NEUROSURGERY QUARTERLY, vol.11, no.2, pp.96-111, 2001 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Review
  • Volume: 11 Issue: 2
  • Publication Date: 2001
  • Doi Number: 10.1097/00013414-200106000-00003
  • Journal Name: NEUROSURGERY QUARTERLY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.96-111
  • Bursa Uludag University Affiliated: Yes

Abstract

During the past decade, it has been repeatedly shown that mild to moderate hypothermia (32-34 degreesC) reduces neurologic injury in animal models of focal or global ischemia, and of traumatic injury. This has led to renewed interest in the application of hypothermia for managing head injury, stroke, and cardiac arrest and for undertaking aneurysm surgery. This article reviews the relevant literature and presents the authors' experience with intracerebral hemorrhage treated under hypothermia.