Morning blood pressure surge in early autosomal dominant polycystic kidney disease and its relation with left ventricular hypertrophy

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Yıldız A., Sag S., Gul C. B., Gullulu S., Can F. E., Bedir O., ...Daha Fazla

RENAL FAILURE, sa.1, ss.223-230, 2021 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1080/0886022x.2020.1864403
  • Dergi Adı: RENAL FAILURE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database, Directory of Open Access Journals
  • Sayfa Sayıları: ss.223-230
  • Anahtar Kelimeler: Autosomal dominant polycystic kidney disease, left ventricular hypertrophy, endothelial dysfunction, morning blood pressure surge
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Introduction: The activation of the sympathetic nervous system, which usually leads to a swift surge in blood pressure in the morning hours (MBPS) may be the cause of left ventricular hypertrophy (LVH) and endothelial dysfunction (ED) in early autosomal dominant polycystic kidney disease (ADPKD) patients. We studied the association between MBPS and LVH in ADPKD patients with preserved renal functions. Methods: Patients with ADPKD with preserved renal functions were enrolled. Prewaking MBPS was calculated using ambulatory blood pressure monitoring. The patients were categorized as MBPS (>= median) and non-MBPS (