Potential use of multi-strain synbiotics for improving postnatal head circumference


Varal I. G. , Koksal N. , ÖZKAN H. , Bagci O., Dogan P.

PAKISTAN JOURNAL OF MEDICAL SCIENCES, vol.34, no.6, pp.1502-1506, 2018 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 34 Issue: 6
  • Publication Date: 2018
  • Doi Number: 10.12669/pjms.346.16107
  • Title of Journal : PAKISTAN JOURNAL OF MEDICAL SCIENCES
  • Page Numbers: pp.1502-1506
  • Keywords: Neurodevelopment, Newborn, Synbiotics, BRAIN-DEVELOPMENT, PRETERM INFANTS, NEURODEVELOPMENT, PROBIOTICS, PREMATURE, GROWTH, SYSTEM

Abstract

Background & Objective: Preterm infants need nutritional and medical requirements in accordance with the physiologic maturity at birth and maintaining optimal postnatal corporal and cerebral growth is one of the main targets of medical caregivers. However, only a few strategies exist to improve the outcomes of infants in a pathogen-rich and nutrient-poor neonatal intensive care unit environment. In this pilot study, we hypothesize that synbiotics may enhance brain growth, which is reflected indirectly by an increase in head circumference through several signalling molecules.