A patient with tyrosine kinase 2 deficiency without hyper-IgE syndrome.

Kilic, SARA; Hacimustafaoglu, MUSTAFA; Boisson-Dupuis, Stephanie; Kreins, Alexandra; Grant, Audrey; Abel, Laurent; Casanova, Jean-Laurent

doi:10.1016/j.jpeds.2012.01.056

A patient with tyrosine kinase 2 deficiency without hyper-IgE syndrome.

Kilic S. Ş., Hacimustafaoglu M. K., Boisson-Dupuis S., Kreins A. Y., Grant A. V., Abel L., ...Daha Fazla

The Journal of pediatrics, cilt.160, sa.6, ss.1055-7, 2012 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 160 Sayı: 6
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.jpeds.2012.01.056
Dergi Adı: The Journal of pediatrics
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.1055-7
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

We describe a Turkish patient with tyrosine kinase 2 deficiency who suffered from disseminated Bacille Calmette-Guerin infection, neurobrucellosis, and cutaneous herpes zoster infection. Tyrosine kinase 2 deficiency should be considered in patients susceptible to herpes viruses and intramacrophage pathogens even in the absence of atopy, high serum IgE, and staphylococcal disease. (J Pediatr 2012; 160:1055-7)