Higher serum nitrate levels are associated with poor survival in lung cancer patients

Colakogullari, Mukaddes; Ulukaya, Engin; Yilmaztepe, ARZU; Ocakoglu, GÖKHAN; Yilmaz, Meryem; Karadag, MEHMET; Tokullugil, Asuman

doi:10.1016/j.clinbiochem.2006.06.008

Higher serum nitrate levels are associated with poor survival in lung cancer patients

Colakogullari M., Ulukaya E., Yilmaztepe A., Ocakoglu G., Yilmaz M., Karadag M., ...Daha Fazla

CLINICAL BIOCHEMISTRY, cilt.39, sa.9, ss.898-903, 2006 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 39 Sayı: 9
Basım Tarihi: 2006
Doi Numarası: 10.1016/j.clinbiochem.2006.06.008
Dergi Adı: CLINICAL BIOCHEMISTRY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.898-903
Anahtar Kelimeler: nitric oxide (NO), vascular endothelial growth factor-A (VEGF-A), lung cancer, survival, serum nitrite/nitrate, ENDOTHELIAL GROWTH-FACTOR, NITRIC-OXIDE SYNTHASE, P53 GENE MUTATION, SMALL-CELL, ANGIOGENESIS, EXPRESSION, METASTASIS, CISPLATIN, ROLES, ACTIVATION
Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objectives: Angiogenic factors induce tumour growth and angiogenesis which leads to tumour metastasis and a poor survival rate. This study aimed to assess the possible roles of nitric oxide (NO) and vascular endothelial growth factor-A (VEGF-A) in the overall survival of patients with late stage lung cancer.