Higher serum nitrate levels are associated with poor survival in lung cancer patients

Colakogullari, Mukaddes; Ulukaya, Engin; Yilmaztepe, ARZU; Ocakoglu, GÖKHAN; Yilmaz, Meryem; Karadag, MEHMET; Tokullugil, Asuman

doi:10.1016/j.clinbiochem.2006.06.008

Higher serum nitrate levels are associated with poor survival in lung cancer patients

Colakogullari M., Ulukaya E., Yilmaztepe A., Ocakoglu G., Yilmaz M., Karadag M., ...More

CLINICAL BIOCHEMISTRY, vol.39, no.9, pp.898-903, 2006 (SCI-Expanded, Scopus)

Publication Type: Article / Article
Volume: 39 Issue: 9
Publication Date: 2006
Doi Number: 10.1016/j.clinbiochem.2006.06.008
Journal Name: CLINICAL BIOCHEMISTRY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.898-903
Keywords: nitric oxide (NO), vascular endothelial growth factor-A (VEGF-A), lung cancer, survival, serum nitrite/nitrate, ENDOTHELIAL GROWTH-FACTOR, NITRIC-OXIDE SYNTHASE, P53 GENE MUTATION, SMALL-CELL, ANGIOGENESIS, EXPRESSION, METASTASIS, CISPLATIN, ROLES, ACTIVATION
Bursa Uludag University Affiliated: Yes

Abstract

Objectives: Angiogenic factors induce tumour growth and angiogenesis which leads to tumour metastasis and a poor survival rate. This study aimed to assess the possible roles of nitric oxide (NO) and vascular endothelial growth factor-A (VEGF-A) in the overall survival of patients with late stage lung cancer.