Effect of Cordyceps militaris on formation of short-chain fatty acids as postbiotic metabolites

Omak G., YILMAZ ERSAN L.

PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY, vol.52, no.10, pp.1142-1150, 2022 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 52 Issue: 10
  • Publication Date: 2022
  • Doi Number: 10.1080/10826068.2022.2033992
  • Journal Name: PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Agricultural & Environmental Science Database, Applied Science & Technology Source, BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, EMBASE, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1142-1150
  • Keywords: Cordyceps militaris, Lactobacillus, postbiotics, prebiotic, probiotic, SCFAs, INTERNATIONAL SCIENTIFIC ASSOCIATION, CONSENSUS STATEMENT, PREBIOTIC ACTIVITY, ORGANIC-ACIDS, POLYSACCHARIDES, FERMENTATION, ANTIOXIDANT, MUSHROOMS, PROBIOTICS, MICROBIOTA
  • Bursa Uludag University Affiliated: Yes

Abstract

The aim of the current study was to determine the growth-promoting-effect of Cordyceps militaris, known as a medicinal mushroom, on Lactobacillus casei and Lactobacillus acidophilus. To evaluate the best growth-promoting activity of the test substrates including glucose, inulin, and at different concentrations of C. militaris (0.5%, 1%, and 2%), the cell counts, optical density (OD), prebiotic activity scores, and postbiotics (lactic, acetic, butyric, and propionic acids) were determined. The highest cell count was found for L. casei in media containing 0.5% C. militaris and for L. acidophilus in media containing 1% C. militaris. In the case of both strains, the OD values of the medium with C. militaris (1%) and (2%) increased similar to those of glucose. The prebiotic activity scores for both strains were positive. The concentration of lactic acid ranged from 0.56 to 8.07 g L-1 for L. casei and 0.82 to 5.38 g L-1 for L. acidophilus. Moreover, propionic acid was the highest among short-chain fatty acids (SCFAs) produced by both strains. According to the results of the present study, the tested Lactobacillus species can utilize C. militaris as carbon source and is able to form postbiotics in the media.