Ertapenem plus meropenem combination treatment in carbapenem-resistant Klebsiella pneumoniae bacteremia: an analysis of 53 cases.


Önal U., Akyol D., Kaya A., Başkol D., Kenanoglu B., Şanlıdağ G., ...More

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, vol.42, pp.1269-1273, 2023 (SCI-Expanded) identifier identifier identifier

Abstract

Herein, we aimed to describe the outcomes of patients with blood stream infections due to carbapenem-resistant Klebsiella pneumoniae (CR-Kp) who received ertapenem plus meropenem combination treatment (EMCT). A total of 53 patients with culture proven CR-Kp bacteremia treated with ertapenem + meropenem were included. The patients with secondary bacteremia due to urinary tract infection exhibited a significantly lower 1-month mortality (OMM), particularly in those with microbiological eradication and those with end-of-treatment success. Salvage EMCT resulted in 49% 1-month survival.