Ki-67 proliferation index in renal biopsy samples of patients with systemic lupus erythematosus and its correlation with clinical findings.

Dalkilic E., Filiz G., YAVUZ M., DİLEK K., ERSOY A., Yurtkuran M., ...Daha Fazla

Iranian journal of kidney diseases, cilt.7, sa.3, ss.198-203, 2013 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 7 Sayı: 3
  • Basım Tarihi: 2013
  • Dergi Adı: Iranian journal of kidney diseases
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.198-203
  • Anahtar Kelimeler: Ki-67 antigen, systemic lupus erythematosus, kidney pathology, SMOOTH MUSCLE ACTIN, NUCLEAR ANTIGEN, OVARIAN-CANCER, MARKER KI-67, EXPRESSION, GLOMERULONEPHRITIS, APOPTOSIS, CLASSIFICATION, NEPHRITIS, PROTEIN
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Introduction. Systemic lupus erythematosus is an autoimmune disease that may affect almost all organ systems. Renal involvement is the most significant prognostic factor. Renal biopsy findings play an important role in treatment decision. Ki-67 is a monoclonal antibody that is only found in proliferative cells. This study aimed to investigate the proliferative activity in renal biopsy specimens of patients with lupus nephritis using the Ki-67 monoclonal antibody, and to compare the proliferative index between different subgroups of patients.