Maksimal egzersizin fibrinolitik aktivite ve kan hücreleri üzerine etkisi

Tez Türü: Tıpta Uzmanlık

Tezin Yürütüldüğü Kurum: Bursa Uludağ Üniversitesi, Tıp Fakültesi, Temel Tıp Bilimleri, Türkiye

Tez Danışmanı: Kasım Özlük

Tezin Onay Tarihi: 1994

Tezin Dili: Türkçe

Özet:

The purpose of this study was to investigate changes in fibrinolytic activity (FA) during the recovery period of maximal exercise (MEx) in sedantary males. Sixteen healthy, nonsmoker volunteers aged 23.2 (19-30) is volunteered. VO2max, body surface area (BSA) and body fat percentage is calculated for all subjects. They performed maximal cycling exercise to exhaustion. Euglobulin lysis time (ELT), fibrin plate lysis area (FPLA), fibrinogen (F), tissue-type plasminogen activator (tPA), pH, lactate (L), cholesterol(Ch), and triglyceride (Tr) concentrations measured before the exercise (BE), immediately after exercise (AE), one (1AE) and four (4AE) hours after the exercise. The results of FPLA, tPA increased at AE and 1AE while they decreased at 4AE. ELT decreased at IAE and 1AE, but it increased at 4AE. However, F values didn't change significantly during the same period. FA changes didn't correlate to VO2max., BSA, % body fat, pH, L, Ch, Tr concentrations. In conclusion, the results of the study indicated that FA changes seen immediately AE is still continuing during the recovery period. The decrease in FA at 4AE reminded us that it could be one of the mechanisms of the sudden death encountered after intense stress or exertions.