Tez Türü: Tıpta Uzmanlık
Tezin Yürütüldüğü Kurum: Diğer (Kurumlar,hastaneler Vb.), Konya Eğitim Araştıma Hastanesi , DAHİLİ Tıp Bilimleri, Türkiye
Tez Danışmanı: Şükrü Arslan
Tezin Onay Tarihi: 2014
Tezin Dili: Türkçe
Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
Desteklendiği Program: Diğer
Özet:
Objective Lower respiratory tract infections (LRTI) are one of the most important
causes of morbidity and mortality in childhood. Hypoxemia, pulmonary hypertension
(PH) due to pulmonary vasoconstriction, and heart failure due to various causes are the
most important risk factors for mortality in LRTI. The aim of this study was to
investigate characteristics of the patients with LRTI and the frequency of PH that
developed secondary to LRTI.
Materials and Methods The study included 70 patients who were diagnosed as
having LRTI clinically and radiologically between January 2012 and March 2013 at
Department of Pediatrics, Konya Training and Research Hospital. Age, sex, risk factors
for LRTI, symptoms and physical examination findings, laboratory tests, and Doppler
echocardiography findings of the patients were retrospectively reviewed.
Results Of the patients, 44 (62.9%) weremale and 26 (37.1%) were female. Thirty-seven
(52.9%) patients were younger than 1 year, and the mean age was 2.53.11 years. The
most common symptoms of the patients were cough and fever. Rhonchus, retraction, and
crackleswere found to be themost common findings in physical examinations.Heart failure
was found in 10% of patients and PH was detected in 8.6% through Doppler echocardiography.
Development of heart failure and the presence of bilateral patch infiltration on
posteroanterior chest X-rays were significantly more frequent in patients with PH. Some
42.9% of patients had at least one viral agent in their nasopharyngeal swabs. The most
common viral agents were respiratory syncytial virus and rhinoviruses.
Conclusion PH may develop during the course of LRTI in children. Given that the
development of PH can cause life-threatening complications such as heart failure,
affected patients should be kept under close follow-up. It should be remembered that
PH is more likely to develop in patients with bilateral patch infiltration on chest X-ray.