The Frailty of Advanced Kidney Disease: The Role of Mitochondria


YILDIZ A., Ikizler T. A.

TURKISH JOURNAL OF NEPHROLOGY, vol.31, no.3, pp.190-193, 2022 (ESCI) identifier identifier identifier

  • Publication Type: Article / Review
  • Volume: 31 Issue: 3
  • Publication Date: 2022
  • Doi Number: 10.5152/turkjnephrol.2022.22317
  • Journal Name: TURKISH JOURNAL OF NEPHROLOGY
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.190-193
  • Keywords: Chronic kidney disease, mitochondria, muscles
  • Bursa Uludag University Affiliated: Yes

Abstract

Uremic toxins contribute to the impairment of mitochondrial function that subsequently could result in organ failure. Mitochondrial dysfunction also plays an essential role in the pathogenesis of sarcopenia in chronic kidney disease patients. It may be feasible to assess the effect of mitochondrial-targeted drugs to treat sarcopenia in patients with chronic kidney disease.