The presence of Helicobacter pylori in cervical preinvasive lesions

Kaya T., Ozan H., Ozakin C.

CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY, cilt.36, sa.2, ss.113-115, 2009 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 36 Sayı: 2
  • Basım Tarihi: 2009
  • Dergi Adı: CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.113-115
  • Anahtar Kelimeler: Helicobacter pylori, Cervix, INFECTION, CANCER, TRANSMISSION, ASSOCIATION, PREVALENCE, RISK
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Purpose: Helicobacter pylori (H. pylori) is believed to play a role in several gynecological and obstetric pathologies since the cervical mucosa resembles the gastric environment. The microorganism is expected to infect the upper genital tract via the oral-genital and fecal-genital routes. Methods: We studied 35 cases with benign, ASCUS, ASC-H, LSIL and HSIL pap-smear results. The presence of H. pylori in the uterine cervix and active infection were investigated with the H. pylori stool antigen test. Biopsy specimens were stained with hemnatoxylin-eosin and Warthin-Starry stains to find H. pylori in cervical tissue. Seroprevalence was investigated by using ELISA for H. pylori IgG and IgA. Results: The H. pylori seroprevalence was 65.7%; further, 17.1% of the cases had an active infection. H. pylori was not found in the cervix or the cervicovaginal secretions. Conclusion: The cervix is not a reservoir for H. pylori, and the microorganism does not appear to be transmitted through the fecal-genital route.