Anxiety and depression in Ankylosing spondylitis patients Anki̇lozan spondi̇li̇tli̇ hastalarda anksi̇yete ve depresyon

ALTAN İNCEOĞLU L., Bingöl Ü., Sarandöl A., Aslan M., ERCAN İ., Yurtkuran M.

Journal of Rheumatology and Medical Rehabilitation, vol.14, no.4, pp.221-227, 2003 (Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 14 Issue: 4
  • Publication Date: 2003
  • Journal Name: Journal of Rheumatology and Medical Rehabilitation
  • Journal Indexes: Scopus
  • Page Numbers: pp.221-227
  • Keywords: Ankylosing spondylitis, Anxiety, Depression
  • Bursa Uludag University Affiliated: Yes


Objective: To compare the incidence of anxiety and depressive disorder in Ankylosing spondylitis (AS) patients with healthy control group and to investigate the correlation between psychiatric disorder level and activation parameters of rheumatologic disease. Method: One group of 63 consecutive AS patients and another group of 60 healthy control individuals, both with the same age average, were asked to fill 'Symptom Checklist 90 (SCL-90-R)', 'Beck Depression Inventory (BDI)' and 'Hospital Anxiety and Depression Inventory (HAD)' to investigate psychiatric symptoms. The values obtained in both groups were compared. Then, correlations between depression and anxiety symptoms and the parameters of disease duration, daytime and nocturnal pain, morning stiffness, global evaluation of the patient and physician, and Schober test were assessed in AS patients. Results: The points obtained by BDE were above 17 (the cut-off point) in 14.3% of AS patients and in 9.4% of the control group. According to HAD, depression and anxiety symptoms existed in 33.3% and 24.5% of the AS patients, respectively, while these rates were 24.5% for depression and 14.3% for anxiety in the control group. GSI points were above 1 (the cut-off point) in 31.7% of AS patients and in 34% of the control group. The comparison of the two groups showed no significant difference for any parameter except for HAD anxiety parameter (p<0.01). It was found that BDE was in significant correlation with daytime and nocturnal pain (p<0.01) in AS patients. Correlation was also significant between PSDI-daytime and nocturnal pain (p<0.01), morning stiffness (p<0.01), disease duration (p<0.05) and between HAD anxiety score- night pain (p<0.05). Conclusion: Our study showed that anxiety is significantly higher in AS patients than in healthy people and there is a positive correlation between the clinical parameters of disease and both depression and anxiety.