Retrospective Evaluation of Colistin-Resistant Isolates in Automated System by Gradient Diffusion Method and Broth Microdilution Method

Tüzemen N. Ü., Efe K., Akalin H., Özakın C.

KLIMIK JOURNAL, cilt.32, sa.1, ss.57-61, 2019 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 32 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.5152/kd.2019.13
  • Dergi Adı: KLIMIK JOURNAL
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.57-61
  • Anahtar Kelimeler: Colistin, antibiotic susceptibility testing, drug resistance, SUSCEPTIBILITY TESTING METHODS, AGAR DILUTION, DISC DIFFUSION, ANTIMICROBIAL ACTIVITY, VITEK 2, ETEST, TIGECYCLINE, PNEUMONIAE, MECHANISMS, MICROSCAN
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Objective: Optimizing colistin susceptibility testing has difficulties because of its high molecular weight and high binding capacity to polystyrene which is frequently used in antibiotic susceptibility testing. We aimed to compare the results of isolates, which were detected as colistin-resistant in the automated system, obtained by using broth microdilution (BMD) method which is the gold standard, with gradient diffusion method (GDM).