Effects of long-term consumption of high fructose corn syrup containing peach nectar on body weight gain in sprague dawley rats


ÖZCAN SİNİR G. , SUNA S. , Inan S., Bagdas D., TAMER C. E. , ÇOPUR Ö. U. , ...More

FOOD SCIENCE AND TECHNOLOGY, vol.37, no.2, pp.337-343, 2017 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 37 Issue: 2
  • Publication Date: 2017
  • Doi Number: 10.1590/1678-457x.25416
  • Title of Journal : FOOD SCIENCE AND TECHNOLOGY
  • Page Numbers: pp.337-343
  • Keywords: HFCS, weight gain, insulin, leptin, BMI, peach nectar, SWEETENED BEVERAGES, INSULIN-RESISTANCE, DIETARY FRUCTOSE, UNITED-STATES, ENERGY-INTAKE, FEMALE RATS, OBESITY, FAT, ENDOCRINE, SUCROSE

Abstract

High fructose corn syrup (HFCS) is one of the most used sweeteners in the food industry. Health concerns regarding the consumption of HFCS-containing foods have developed in parallel with the increasing amount of people who become overweight. This study was conducted to investigate whether HFCS-containing peach nectar (pn-HFCS) consumption has more detrimental effects on anthropometrical and biochemical parameters compared with sucrose-containing peach nectar (pn-sucrose). Fifty-day-old Sprague Dawley rats were divided into three groups and were fed (A) pn-HFCS + ad libitum chow, (B) pn-sucrose + ad libitum chow and (C) only ad libitum chow for 7 months. The percentage change in body weight (PCBW), body mass index (BMI), and Lee index were calculated, and serum triglyceride, glucose, insulin and leptin concentrations were measured. The PCBW, BMI, Lee index, serum triglyceride, glucose, insulin and leptin concentrations were insignificant among the three groups. We can suggest that peach nectar consumption resulted in more energy intake than the control and since pn-HFCS group consumed more chow than the pn-sucrose group. The results show that long term daily HFCS or sucrose consumption in peach nectar is not associated with weight gain and does not stimulate metabolic changes in Sprague Dawley rats.