Vanadyl sulfate, taurine, and combined vanadyl sulfate and taurine treatments in diabetic rats: Effects on the oxidative and antioxidative systems

Tas S., Sarandol E., Ayvalik S., Serdar Z., Dirican M.

ARCHIVES OF MEDICAL RESEARCH, cilt.38, sa.3, ss.276-283, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 38 Sayı: 3
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1016/j.arcmed.2006.09.018
  • Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.276-283
  • Anahtar Kelimeler: streptozotocin, nicotinamide, oxidative stress, paraoxonase, vanadyl sulfate, taurine, ERYTHROCYTE LIPID-PEROXIDATION, HUMAN-SERUM PARAOXONASE, VASCULAR COMPLICATIONS, INSULIN SENSITIVITY, FATTY RAT, IN-VITRO, MELLITUS, STREPTOZOTOCIN, STRESS, METABOLISM
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background. Vanadyl sulfate (VS) and taurine are two promising agents in the treatment of diabetes related to their anti hyperglycemic, antihyperlipidemic, and hyperinsulinemic effects. Data about the effects of VS on the oxidant-antioxidant system is limited and controversial. However, taurine is a well-documented antioxidant agent and our aim was to investigate the effects of VS, taurine and VS and taurine combination on the oxidative-antioxidative systems in streptozotocin-nicotinamide (STZ-NA) diabetic rats.