Prognostic significance of c-erbB2 overexpression in patients with metastatic gastric cancer

Bayrak M., Olmez O. F., Kurt E., ÇUBUKÇU E., EVRENSEL T., Kanat O., ...More

CLINICAL & TRANSLATIONAL ONCOLOGY, vol.15, no.4, pp.307-312, 2013 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 15 Issue: 4
  • Publication Date: 2013
  • Doi Number: 10.1007/s12094-012-0921-0
  • Journal Name: CLINICAL & TRANSLATIONAL ONCOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.307-312
  • Keywords: c-erbB2, Gastric cancer, Metastasis, Immunohistochemistry, Prognosis, EXPRESSION, TRASTUZUMAB, BREAST, HER2
  • Bursa Uludag University Affiliated: Yes

Abstract

Overexpression of the gene c-erbB2, which encodes a receptor tyrosine kinase, has been associated with prognosis and response to therapy in several solid tumors. This study was designed to test whether c-erb-B2 overexpression can be related to prognosis of patients with metastatic gastric cancer.