Helicobacter pylori Infection in Children: Nutritional Status and Associations with Serum Leptin, Ghrelin, and IGF-1 Levels

Erdemir G., ÖZKAN T. M., ÖZGÜR T., Altay D., ÇAVUN S., Goral G.

HELICOBACTER, cilt.21, sa.4, ss.317-324, 2016 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 4
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1111/hel.12288
  • Dergi Adı: HELICOBACTER
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.317-324
  • Anahtar Kelimeler: Childhood, H, pylori, growth, leptin, ghrelin, BODY-MASS INDEX, GROWTH-FACTOR, PEPTIC-ULCERATION, RISK-FACTORS, STOMACH, EPIDEMIOLOGY, MALNUTRITION, ADOLESCENTS, CHILDHOOD, GASTRITIS
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

BackgroundHelicobacter pylori is associated with gastrointestinal diseases such as gastritis, peptic ulcers, malignancy and lymphoma, and extra-gastrointestinal conditions. H. pylori infection is negatively associated with children's growth. Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones such as leptin, and ghrelin are the probable reasons of this negative association. The objective of this study is to determine the serum levels of leptin, ghrelin, and IGF-1 in H. pylori-infected children and their relations with growth.