Paricalcitol Protects Peritoneal Membrane Function in Encapsulating Peritoneal Sclerosis

Gul C. B., YILDIZ A., AYTAÇ VURUŞKAN B., ÖZ GÜL Ö., ORUÇ A., Aktas N., ...More

TURKISH NEPHROLOGY DIALYSIS AND TRANSPLANTATION JOURNAL, vol.25, no.3, pp.283-288, 2016 (ESCI) identifier identifier


OBJECTIVE: The most lethal complication of peritoneal dialysis is encapsulating peritoneal sclerosis (EPS), which develops as a result of epithelio-mesenchymal transformation (EMT) and known fibrotic processes. Paricalcitol has previously been shown to inhibit both EMT and fibrosis. We investigated the effect of paricalcitol on EPS.