Serum monocyte chemoattractant protein-1 and monocyte adhesion molecules in type 1 diabetic patients with nephropathy


Kiyici S., Erturk E., Budak F., Ersoy C., Tuncel E., Duran C., ...Daha Fazla

ARCHIVES OF MEDICAL RESEARCH, cilt.37, sa.8, ss.998-1003, 2006 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 8
  • Basım Tarihi: 2006
  • Doi Numarası: 10.1016/j.arcmed.2006.06.002
  • Dergi Adı: ARCHIVES OF MEDICAL RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.998-1003
  • Anahtar Kelimeler: diabetic nephropathy, MCP-1, adhesion molecules, ENDOTHELIAL DYSFUNCTION, EXPRESSION, RECRUITMENT, MACROPHAGES, ACTIVATION, CHEMOKINES, CYTOKINE, MELLITUS, MARKERS, LESIONS
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background. Monocyte chemoattractant protein (MCP)-1 is suggested to be implicated in the pathogenesis of diabetic nephropathy by activating and recruiting monocytes to the glomerulus via regulation of adhesion molecule expressions. The aim of this study was to test potential associations between serum concentrations of MCP-1, monocyte expression of Mac-1 and LFA-1 and nephropathy in type 1 diabetes mellitus.