Serum leptin and ghrelin levels in response to methylprednisolone injection in healthy dogs.

Yilmaz Z. , Ilcol Y. O. , Golcu E.

Research in veterinary science, vol.82, no.2, pp.187-94, 2007 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 82 Issue: 2
  • Publication Date: 2007
  • Doi Number: 10.1016/j.rvsc.2006.07.005
  • Title of Journal : Research in veterinary science
  • Page Numbers: pp.187-94


The aim of this study was to investigate the effects of methylprednisolone treatment on serum leptin and ghrelin levels in healthy dogs (n = 40). After 14 h of fasting, the dogs were injected intramuscularly with saline (control group) or methylprednisolone (1, 5 or 10 mg/ kg). Blood samples were collected prior to (baseline) and 2, 3, 4, 8, 12 and 24 h subsequent to the treatments. Serum leptin and ghrelin were measured by radioimmunoassay.