ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY, vol.19, no.9, pp.1184-1195, 2019 (Journal Indexed in SCI)
Article / Article
Title of Journal :
ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY
Prostate cancer, cytotoxicity, apoptosis, oxidative stress, unfolded protein response, platinum(II) complex, ENDOPLASMIC-RETICULUM STRESS, HISTONE H2AX PHOSPHORYLATION, N-TERMINAL KINASE, OXIDATIVE STRESS, IN-VITRO, STRUCTURAL-CHARACTERIZATION, CRYSTAL-STRUCTURE, ER STRESS, DNA, DESIGN
Background: Prostate cancer is one of the most common cancer types and it is the sixth leading cause of cancer-related death in men worldwide. Even though novel treatment modalities have been developed, it still a lifethreatening disease. Therefore novel compounds are needed to improve the overall survival.