Potential use of multi-strain synbiotics for improving postnatal head circumference

Varal I. G., Koksal N., ÖZKAN H., Bagci O., Dogan P.

PAKISTAN JOURNAL OF MEDICAL SCIENCES, cilt.34, sa.6, ss.1502-1506, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 6
  • Basım Tarihi: 2018
  • Doi Numarası: 10.12669/pjms.346.16107
  • Dergi Adı: PAKISTAN JOURNAL OF MEDICAL SCIENCES
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1502-1506
  • Anahtar Kelimeler: Neurodevelopment, Newborn, Synbiotics, BRAIN-DEVELOPMENT, PRETERM INFANTS, NEURODEVELOPMENT, PROBIOTICS, PREMATURE, GROWTH, SYSTEM
  • Bursa Uludağ Üniversitesi Adresli: Evet

Özet

Background & Objective: Preterm infants need nutritional and medical requirements in accordance with the physiologic maturity at birth and maintaining optimal postnatal corporal and cerebral growth is one of the main targets of medical caregivers. However, only a few strategies exist to improve the outcomes of infants in a pathogen-rich and nutrient-poor neonatal intensive care unit environment. In this pilot study, we hypothesize that synbiotics may enhance brain growth, which is reflected indirectly by an increase in head circumference through several signalling molecules.