Higher serum nitrate levels are associated with poor survival in lung cancer patients

Colakogullari, Mukaddes; Ulukaya, Engin; Yilmaztepe, ARZU; Ocakoglu, Gokhan; Yilmaz, Meryem; Karadag, Mehmet; Tokullugil, Asuman

doi:10.1016/j.clinbiochem.2006.06.008

Higher serum nitrate levels are associated with poor survival in lung cancer patients

Colakogullari M., Ulukaya E., Yilmaztepe A. , Ocakoglu G., Yilmaz M., Karadag M., ...More

CLINICAL BIOCHEMISTRY, vol.39, no.9, pp.898-903, 2006 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 39 Issue: 9
Publication Date: 2006
Doi Number: 10.1016/j.clinbiochem.2006.06.008
Title of Journal : CLINICAL BIOCHEMISTRY
Page Numbers: pp.898-903
Keywords: nitric oxide (NO), vascular endothelial growth factor-A (VEGF-A), lung cancer, survival, serum nitrite/nitrate, ENDOTHELIAL GROWTH-FACTOR, NITRIC-OXIDE SYNTHASE, P53 GENE MUTATION, SMALL-CELL, ANGIOGENESIS, EXPRESSION, METASTASIS, CISPLATIN, ROLES, ACTIVATION

Abstract

Objectives: Angiogenic factors induce tumour growth and angiogenesis which leads to tumour metastasis and a poor survival rate. This study aimed to assess the possible roles of nitric oxide (NO) and vascular endothelial growth factor-A (VEGF-A) in the overall survival of patients with late stage lung cancer.